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Monster Energy (473ml / 16oz)

Caffeine Half-Life Analysis

For: Liver Impairment
160
mg Caffeine
12.0
Hour Half-Life
~10
Hours to Sleep-Safe
400
mg Daily Limit
bedtime
To sleep well at 10 PM, stop caffeine by:
1:51 PM

trending_down Caffeine Decay Timeline

How 160mg caffeine clears from your system with a 12.0-hour half-life

Time Elapsed Caffeine Remaining % of Original Status
Now (consumption) 160.0 mg
100.0%
Active
After 1 hour 151.0 mg
94.4%
Active
After 2 hours 142.5 mg
89.1%
Active
After 3 hours 134.5 mg
84.1%
Active
After 4 hours 127.0 mg
79.4%
Active
After 5 hours 119.9 mg
74.9%
Active
After 6 hours 113.1 mg
70.7%
Active
After 8 hours 100.8 mg
63.0%
Active
After 10 hours 89.8 mg
56.1%
Moderate
After 12 hours 80.0 mg
50.0%
Moderate
After 16 hours 63.5 mg
39.7%
Moderate
After 20 hours 50.4 mg
31.5%
Moderate
After 24 hours 40.0 mg
25.0%
Minimal

health_and_safety Health Insights for Liver Impairment

⚠️ Important Health Consideration

Conditions like cirrhosis or hepatitis reduce the liver's ability to produce CYP1A2 enzymes. Caffeine can remain in the system 2-3x longer than normal.

Daily Limit Calculation

  • Recommended daily limit: 400mg of caffeine
  • Caffeine per serving: 160mg
  • Servings until limit: 2.5 servings

Consult your physician about caffeine intake. Consider limiting to 100mg/day or less.

Sleep Quality Impact

Caffeine blocks adenosine receptors in the brain, preventing the buildup of sleep pressure. Even when you don't feel "wired," residual caffeine can reduce deep sleep quality by up to 20%.

>100mg
May disrupt sleep
50-100mg
Reduced deep sleep
<50mg
Minimal impact

science How Caffeine Half-Life Works

Half-life is the time required for the body to eliminate 50% of a substance. For caffeine, this primarily occurs in the liver through the CYP1A2 enzyme system.

With a half-life of 12.0 hours for liver impairment, caffeine follows exponential decay:

  • After 12.0 hours: 50% remains (80.0mg)
  • After 24.0 hours: 25% remains (40.0mg)
  • After 36.0 hours: 12.5% remains (20.0mg)
  • After 48.0 hours: 6.25% remains (10.0mg)

The liver impairment category has a slower metabolism compared to healthy adults (5 hours baseline). Conditions like cirrhosis or hepatitis reduce the liver's ability to produce CYP1A2 enzymes. Caffeine can remain in the system 2-3x longer than normal.

warning Important Health Notice

Consult your physician about caffeine intake. Consider limiting to 100mg/day or less.

About Monster Energy (473ml / 16oz)

Large format energy drink

Note: One can contains nearly the recommended daily limit

help Frequently Asked Questions

How long does Monster Energy (473ml / 16oz) caffeine last for liver impairment?

For liver impairment, the caffeine half-life is approximately 12.0 hours. This means that 160mg of caffeine from Monster Energy (473ml / 16oz) will take about 12.0 hours to reduce to 80mg, and 24.0 hours to drop to 40mg. Full clearance (below 10mg) takes approximately 48.0 hours.

When should I stop drinking Monster Energy (473ml / 16oz) to sleep well?

If you plan to sleep at 10 PM, you should consume your last Monster Energy (473ml / 16oz) by 1:51 PM. This allows approximately 8.1 hours for caffeine levels to drop below the sleep disruption threshold of 100mg.

How does being in the 'Liver Impairment' category affect caffeine metabolism?

Conditions like cirrhosis or hepatitis reduce the liver's ability to produce CYP1A2 enzymes. Caffeine can remain in the system 2-3x longer than normal. Consult your physician about caffeine intake. Consider limiting to 100mg/day or less.